Gijzen, Mark, Ph.D.

• Research Publications
• Other Science Related Publications

Contact Information:

1391 Sandford St
London, Ontario N5V 4T3
Telephone: 519-457-1470 (280)
Fax: 519-457-3997
Email: mark.gijzen@agr.gc.ca

Areas of Expertise:

• Molecular plant pathology and plant molecular biology; the application of modern methods of molecular genetic analysis to discover associations between genes and traits; the construction and sampling of cDNA libraries for expressed sequence tags; transcript profiling using microarrays; identification of genes by map-based approaches; biochemical characterization of protein toxins and elicitors; genomics.
• Disease Resistance - Root rot caused by Phytophthora sojae is a serious and ongoing disease problem for Canadian soybean growers. Research efforts concentrate on identifying pathogen factors that determine host range and virulence
• Soybean Seed Quality - Seed quality characteristics affect the value and utilization of the crop and are important to importers, crushers, processors, seed dealers, and consumers of soy-based products. Our research focuses specifically on quality traits that are determined by the seed coat and pericarp tissues

Current Projects:

• Plant Pathogenic Phytophthora: Molecular Determinants of Virulence and Pathogenicity
• Soybean Seed Coat Proteins: Molecular Determinants of Quality and Allergenicity

Affiliations:

• Adjunct Professor, University of Western Ontario

Research Publications:

2013:

• Qutob, D., Chapman, B. P., and Gijzen, M. (2013). "Transgenerational gene silencing causes gain of virulence in a plant pathogen.", Nature Communications, 4:1349. doi : 10.1038/ncomms2354

2012:

• Dong, S., Kong, G., Qutob, D., Yu, X., Tang, J., Kang, J., Dai, T., Wang, H., Gijzen, M., and Wang, Y. (2012). "The NLP Toxin Family in Phytophthora sojae Includes Rapidly Evolving Groups That Lack Necrosis-Inducing Activity.", Molecular Plant-Microbe Interactions, 25(7), pp. 896-909. doi : 10.1094/MPMI-01-12-0023-R

2011:

• Chowda-Reddy, R.V., Sun, H., Chen, H., Poysa, V., Ling, H., Gijzen, M., and Wang, A.M. (2011). "Mutations in the P3 Protein of Soybean mosaic virus G2 Isolates Determine Virulence on Rsv4-Genotype Soybean.", Molecular Plant-Microbe Interactions, 24(1), pp. 37-43. doi : 10.1094/MPMI-07-10-0158
• Dong, S., Yin, X., Kong, G., Yang, X., Qutob, D., Kale, S.D., Chen, Q., Sui, Y., Zhang, Z., Dou, D., Zheng, X., Gijzen, M., Tyler, B.M., and Wang, Y. (2011). "Phytophthora sojae avirulence effector Avr3b is a secreted NADH and ADP-ribose pyrophosphorylase that modulates plant immunity.", PLoS Pathogens, 7(11, Article No. e1002353). doi : 10.1371/journal.ppat.1002353
• Dong, S., Yu, D., Cui, L., Qutob, D., Tedman-Jones, J., Kale, S.D., Tyler, B.M., Wang, Y., and Gijzen, M. (2011). "Sequence variants of the Phytophthora sojae RXLR effector Avr3a/5 are differentially recognized by Rps3aand Rps5 in soybean.", PLoS ONE, 6(7, Article No. e20172). doi : 10.1371/journal.pone.0020172
• Reiss, K., Kirchner, E., Gijzen, M., Zocher, G., Löffelhardt, B., Nürnberger, T., Stehle, T., and Brunner, F. (2011). "Structural and phylogenetic analyses of the GP42 transglutaminase from Phytophthora sojae reveal an evolutionary relationship between oomycetes and marine Vibrio bacteria.", Journal of Biological Chemistry, 286(49), pp. 42585-42593. doi : 10.1074/jbc.M111.290544
• Ye, W., Wang, X., Tao, K., Lu, Y., Dai, T., Dong, S., Dou, D., Gijzen, M., and Wang, Y. (2011). "Digital gene expression profiling of the Phytophthora sojae transcriptome.", Molecular Plant-Microbe Interactions, 24(12), pp. 1530-1539. doi : 10.1094/MPMI-05-11-0106

2010:

• Dhaubhadel, S., Marsolais, F., Tedman-Jones, J., and Gijzen, M. (2010). "Functional Genomics - Transcriptomics in Soybean.", in Bilyeu, K., Ratnaparkhe, M., and Kole, C. (eds.) - Genetics, Genomics and Breeding of Soybean. Series: Genetics, Genomics and Breeding of Crop Plants, Science Publishers and CRC Press, Chapter 9, pp. 199-222.
• Ranathunge, K., Shao, S., Qutob, D., Gijzen, M., Peterson, C.A., and Bernards, M.A. (2010). "Properties of the soybean seed coat cuticle change during development.", Planta, 231(5), pp. 1171-1188. doi : 10.1007/s00425-010-1118-9

2009:

• Dong, S., Qutob, D., Tedman-Jones, J., Kuflu, K., Wang, Y., Tyler, B.M., and Gijzen, M. (2009). "The Phytophthora sojae Avirulence Locus Avr3c Encodes a Multi-Copy RXLR Effector with Sequence Polymorphisms among Pathogen Strains.", PLoS ONE, 4(5, Article No. e5556). doi : 10.1371/journal.pone.0005556
• Gijzen, M. (2009). "Runaway repeats force expansion of the Phytophthora infestans genome (Review).", Genome Biology, 10(10), pp. 241. doi : 10.1186/gb-2009-10-10-241
• Lewinsohn, E. and Gijzen, M. (2009). "Phytochemical diversity: The sounds of silent metabolism.", Plant Science, 176(2), pp. 161-169. doi : 10.1016/j.plantsci.2008.09.018
• Qutob, D., Tedman-Jones, J., Dong, S., Kuflu, K., Pham, H., Wang, Y., Dou, D., Kale, S.D., Arredondo, F.D., Tyler, B.M., and Gijzen, M. (2009). "Copy number variation and transcriptional polymorphisms of Phytophthora sojae RXLR effector genes Avr1a and Avr3a.", PLoS ONE, 4(4, Article No. e5066). doi : 10.1371/journal.pone.0005066

Other Science Related Publications:

2009:

• Gijzen, M. and Qutob, D. (2009). "Phytophthora sojae and Soybean.", in Lamour, K. and Kamoun, S. (eds.) - Oomycete Genetics and Genomics: Diversity, Interactions, and Research Tools, Wiley - Blackwell, Chapter 15, pp. 303-331.
• Qutob, D., Dong, S., Tedman-Jones, J., Tyler, B.M., and Gijzen, M. (2009). "Gene duplication and copy number variation drives the evolution of Phytophthora RXLR effectors.", 14th International Congress on Molecular Plant-Microbe Interactions, Centre des congrès de Québec, Québec City, QC, Canada, July 19-23, 2009.
• Walton, J.D., Avis, T.J., Alfano, J.R., Gijzen, M., Spanu, P., Hammond-Kosack, K., and Sánchez, F. (2009). "Effectors, Effectors et encore des Effectors: The XIV International Congress on Molecular-Plant Microbe Interactions, Quebec (Meeting review).", Molecular Plant-Microbe Interactions, 22(12), pp. 1479-1483.